Health and Science

"The CDC has advised that large in-person events, particularly in settings where participants do not wear masks or practice social distancing, pose a substantial risk of further contagion (Centers for Disease Control and Prevention, 2020). There is reason to fear that such gatherings can serve as 'superspreader events,' severely undermining efforts to control the pandemic. The purpose of this study is to shed light on these issues by studying the impact of election rallies held by President Donald Trump’s campaign between June 20th and September 30th, 2020. Trump rallies have several distinguishing features that lend themselves to this inquiry. The degree of compliance with guidelines concerning the use of masks and social distancing was low, in part because the Trump campaign downplayed the risk of infection. This feature heightens the risk that a rally could become a 'superspreader event.'” more »

Ahead of the annual Affordable Care Act (ACA) open enrollment period, the time during which consumers can shop for health plans or renew existing coverage, KFF has updated its Health Insurance Marketplace Calculator and its searchable collection of more than 300 Frequently Asked Questions about open enrollment, the health insurance marketplaces and the ACA. KFF’s Health Insurance Marketplace Calculator provides estimates of 2021 health insurance premiums and subsidies for people purchasing insurance on their own in health insurance exchanges. Users can enter age, income, and family size information to estimate their eligibility for subsidies and how much they can expect to spend on health insurance. more »

A newly developed light-sensing protein called the MCO1 opsin restores vision in blind mice when attached to retina bipolar cells using gene therapy. The National Eye Institute, part of the National Institutes of Health, provided a Small Business Innovation Research grant to Nanoscope, LLC for development of MCO1. The company is planning a U.S. clinical trial for later this year. “The beauty of our strategy is its simplicity,” said Samarendra Mohanty, Ph.D., Nanoscope founder and corresponding author of a report on the mouse study that appears today in Nature Gene Therapy. “Bipolar cells are downstream from the photoreceptors, so when the MCO1 opsin gene is added to bipolar cells in a retina with nonfunctioning photoreceptors, light sensitivity is restored.” ... However, no one knows how the restored vision will compare to normal vision. more »

A COVID-19 vaccine or vaccines may become available in the United States in the next several months, at which point the process of actually delivering vaccines to most, if not all, of the population will begin. Although the U.S. has some experience with mass vaccine distribution, including during an outbreak, COVID-19 represents an unprecedented challenge that will require a scale not previously undertaken. Planning has already been underway, including the release of a federal distribution strategy and the federal government’s advance purchase of millions of doses of COVID-19 vaccine candidates. more »