Health, Fitness and Style

In high school, after reading novels by C. P. Snow describing academic life at Cambridge University in England, I decided that I wanted to be a professor (little did I know that this vision of academic life was nothing like reality, at least in the US). In sophomore year, my inner-city high school biology teacher taught us about the experiments of Jan Baptist van Helmont (1579–1644) showing that a piece of soiled cloth mixed with wheat yielded mouse pups after a 21-day incubation. This sealed the deal — I wanted to be a biologist. more »

Joan L. Cannon wrote: "Most people are uncomfortable in the presence of what they see as authority. That’s the way most patients see their doctors. Subtleties like the relative position of the authority figure who sits on a stool a little below the level of the patient’s chair help to alleviate this artificial distance, but a common understanding of human behavior based on a lot more than one person can acquire through direct experience can be the biggest help of all. Once in practice, few doctors will have time for artistic or literary excursions, so it probably would be a good idea to give them as much of that experience as possible as early as possible." more »

The Cancer Genome Atlas (TCGA) final paper details genomic alterations in 10 key signaling pathways that control the stages of the cell’s life cycle, growth, and death. The researchers found that 89% of tumors had at least one significant alteration in these pathways. About 57% of tumors had at least one alteration that could be targeted with currently known drugs and 30% had multiple targetable alterations. These findings will help researchers explore treatments with more tailored approaches, such as using a combination of drugs to target multiple pathways at the same time. more »

Almost all mammals communicate using sound, but few species produce complex songs. Two baleen whales sing complex songs that change annually, though only the humpback whale has received much research attention. This study focuses on the other baleen whale singer, the bowhead whale. Members of the Spitsbergen bowhead whale population produced 184 different song types over a 3-year period, based on duty-cycled recordings from a site in Fram Strait in the northeast Atlantic. Nor is it known if individual bowhead whales maintain the same song throughout their lifetime or if they switch within and/or between years. more »