Culture and Arts

Aduhelm, a new Alzheimer’s drug approved by the Food and Drug Administration last month, could be prescribed to 1 million to 2 million patients a year, even if conservative criteria were used, according to Biogen and Eisai, the companies behind the drug. The total annual price tag would come to $56 billion if the average list price, $56,000, is applied to the lower end of the companies’ estimate. That’s a huge sum by any measure — more than the annual budget for the National Institutes of Health (almost $43 billion this year). Yet there’s considerable uncertainty about Aduhelm’s clinical benefits, fueling controversy over its approval. The FDA has acknowledged it’s not clear whether the medication will actually slow the progression of Alzheimer’s disease or by how much. more »

Carol Christ: When I joined the faculty, only 3% of the faculty were women. When I joined the English department, there were 84 faculty in the English department — it was much bigger then than it is now — and there were four women. I was the fourth woman. And I remember whenever I went to an office, people didn’t believe I was a faculty member. Carol Clover: Or, when I went to Harvard, people always thought that I was a secretary in my office. They would just walk in and say, “Would you please type this for me and have it for tomorrow?” Anne Brice: What would you say? Carol Clover: It would be a nice conversation. They were usually apologetic. It was just the way things were." more »

For over fifty years, Lynn Hershman Leeson has created an innovative and prescient body of work that mines the intersections of technology and the self. Known for her groundbreaking contributions to media art, Hershman Leeson has consistently worked with the latest technologies, from Artificial Intelligence to DNA programming, often anticipating the impact of technological developments on society. As the artist posited in 1998, “Imagine a world in which there is a blurring between the soul and the chip, a world in which artificially implanted DNA is genetically bred to create an enlightened and self-replicating intelligent machine, which perhaps uses a human body as a vehicle for mobility.” more »

US economic activity contracted sharply during 2020 as COVID-19 spread and government introduced policies aimed at curbing the virus. Understanding the impact of the pandemic on economic activity as well as the effectiveness and economic impact of health and containment policies has been a major challenge faced by policymakers. The fundamental issue is that economic activity, COVID-19's spread, and health and containment policies are interconnected — they simultaneously influence each other. In a recent working paper, we develop a methodology to investigate the causal linkages among COVID-19's spread, health and containment policies, and economic activity.1 In this two-part essay, we present a nontechnical summary of our approach and main findings. In particular, Part I explains our methods and summarizes how COVID-19 has affected economic activity and government policies. Part II describes the effects of government policies on COVID-19's spread and economic activity. more »